2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-170783
    DXR-IN-4
    		Inhibitor
    DXR-IN-4 (Compound 12a) is the inhibitor for 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). DXR-IN-4 inhibits DXR in Plasmodium falciparum Pf DXR, Escherichia coli Ec DXR, and Mycobacterium tuberculosis Mt DXR with IC50s of 18, 4.9 and 89 nM, respectively. DXR-IN-4 exhibits antimalarial activity that inhibits P. falciparum strains 3D7 and Dd2 with IC50 of 11 μM and 12 μM.
    DXR-IN-4
  • HY-124018
    MMV665852
    		Inhibitor
    MMV665852 is an antischistosomal agent that inhibits worm viability in vitro. MMV665852 reduces worm burden in mice infected with Schistosoma mansoni.
    MMV665852
  • HY-B1327R
    Chlortetracycline (hydrochloride) (Standard)
    Chlortetracycline (hydrochloride) (Standard) is the analytical standard of Chlortetracycline (hydrochloride). This product is intended for research and analytical applications. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic that inhibits the binding of aminoacyl-tRNA to ribosomes.
    Chlortetracycline (hydrochloride) (Standard)
  • HY-120809
    Spiramycin III
    		Inhibitor
    Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect.
    Spiramycin III
  • HY-100593R
    Spiramycin (Standard)
    		Inhibitor
    Spiramycin (Standard) is the analytical standard of Spiramycin. This product is intended for research and analytical applications. Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached.
    Spiramycin (Standard)
  • HY-B1177R
    Crotamiton (Standard)
    		Inhibitor
    Crotamiton (Standard) is the analytical standard of Crotamiton. This product is intended for research and analytical applications.
    Crotamiton (Standard)
  • HY-W011035R
    Dodecamethylpentasiloxane (Standard)
    		Inhibitor
    Dodecamethylpentasiloxane (Standard) is the analytical standard of Dodecamethylpentasiloxane. This product is intended for research and analytical applications. Dodecamethylpentasiloxane is a component of siloxanes and can be used as silicone oil. Dodecamethylpentasiloxane exhibits insecticidal activity against bed bug.
    Dodecamethylpentasiloxane (Standard)
  • HY-169922
    HDAC-IN-82
    		Inhibitor
    HDAC-IN-82 (Compound 18b) is a histone deacetylase (HDAC) inhibitor with selective antiplasmodial and anticancer activity. HDAC-IN-82 shows potent antiproliferative activity and caspase 3/7 activation in cancer cells. HDAC-IN-82 causes hyperacetylation of histone H3 and α-tubulin.
    HDAC-IN-82
  • HY-15980
    GNF179 (Metabolite)
    		Inhibitor
    GNF179 metabolite is the metabolite of GNF179, which is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.
    GNF179 (Metabolite)
  • HY-N11761
    4,5-Dihydropiperlonguminine
    		Inhibitor
    4,5-Dihydropiperlonguminine is a natural product that can be isolated from the seeds of Piper tuberculatum Jacq. (Piperaceae). 4,5-Dihydropiperlonguminine is a insecticide against velvetbean caterpillars.
    4,5-Dihydropiperlonguminine
  • HY-148177
    Sutidiazine
    		Inhibitor
    Sutidiazine (ZY-19489) is an orally active and antimalarial agent. Sutidiazine inhibits parasitemia-induced infection. Sutidiazine shows short half-lives (approximately 7 h) and an exposure effect.
    Sutidiazine
  • HY-107496R
    Imidocarb (dipropionate) (Standard)
    		Inhibitor
    Imidocarb (dipropionate) (Standard) is the analytical standard of Imidocarb (dipropionate). This product is intended for research and analytical applications. Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL.
    Imidocarb (dipropionate) (Standard)
  • HY-124901R
    Tetrasul (Standard)
    		Inhibitor
    Tetrasul (Standard) is the analytical standard of Tetrasul. This product is intended for research and analytical applications. Tetrasul is an acaricide. Tetrasul inhibits Tetranychus urticae and aphids on hops. Tetrasul has also been used in research of erythematous (type one) rosacea.
    Tetrasul (Standard)
  • HY-W158234
    N-Methylbenzo[d]oxazol-2-amine
    		Inhibitor
    N-Methylbenzo[d]oxazol-2-amine (compound 1) is an anthelmintic activity and lower cytotoxicity against T. spiralis adult worm. N-Methylbenzo[d]oxazol-2-amine up-regulates the metabolism of purine, pyrimidine and down-regulates sphingolipid metabolism.
    N-Methylbenzo[d]oxazol-2-amine
  • HY-157037
    OfChi-h-IN-2
    		Inhibitor
    OfChi-h-IN-2 (compound TQ19) is a potent OfChi-h inhibitor with a Ki value of 0.33 μM. OfChi-h-IN-2 can significantly inhibit the growth and development of Ostrinia nubilalis larvae. OfChi-h-IN-2 can be used in agricultural insecticide research.
    OfChi-h-IN-2
  • HY-17581R
    Buparvaquone (Standard)
    		Inhibitor
    Buparvaquone (Standard) is the analytical standard of Buparvaquone. This product is intended for research and analytical applications. Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone.
    Buparvaquone (Standard)
  • HY-B1414R
    Chloroxylenol (Standard)
    Chloroxylenol (Standard) is the analytical standard of Chloroxylenol. This product is intended for research and analytical applications. Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi and viruses.
    Chloroxylenol (Standard)
  • HY-N12077
    Eurycomanol 2-O-β-D-glucopyranoside
    		Inhibitor
    Eurycomanol 2-O-β-D-glucopyranoside (compound 4) is a natural product that can be obtained from Eurycoma longifolia. Eurycomanol 2-O-β-D-glucopyranoside has the potential for anti-malarial research.
    Eurycomanol 2-O-β-D-glucopyranoside
  • HY-B1400R
    Diiodohydroxyquinoline (Standard)
    		Inhibitor
    Diiodohydroxyquinoline (Standard) is the analytical standard of Diiodohydroxyquinoline. This product is intended for research and analytical applications. Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas.
    Diiodohydroxyquinoline (Standard)
  • HY-119459R
    Fluopyram (Standard)
    		Inhibitor
    Fluopyram (Standard) is the analytical standard of Fluopyram (HY-119459). This product is intended for research and analytical applications. Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC50 values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic.
    Fluopyram (Standard)
Parasite Isoform Comparison

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